Cortisone acetate (Cortone) is an acetate salt form of cortisone that is a steroid hormone and a glucocorticoid. Cortisone acetate (Cortone) is used to treat a variety of ailments. Cortisone acetate (Cortone) suppresses the immune system, thus reducing inflammation and attendant pain and swelling at the site of the injury. Cortisone and adrenaline are the main hormones released by the body as a reaction to stress. They elevate blood pressure and prepare the body for a fight or flight response. Cortisone acetate (Cortone) may also be used to deliberately suppress immune response in persons with autoimmune diseases or following an organ transplant to prevent transplant rejection. The suppression of the immune system may also be important in the treatment of inflammatory conditions such as severe IgE-mediated allergies.